The 2500 is the filter with the highest maximum absorption throughout the BlackNoise range, almost equal to a standard Italian domestic energy contract. Hardly you will ever need anything more powerful!
The natural use of the 2500 is with high-power amps where, without absolutely showing any kind of dynamic compression, is able to excert a very effective protection and elimination of mains noises and harmonics. Another very good field of application for the 2500 (alike its smaller sibling, the 1000) is with electrostatic speakers or OTL amps.
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If needed, the 2500 may be used as the only filter in a audio/video setup (in the same manner as the 500 , the 1000 or the MiniBlack) but if your setup absorbs so many Watts that not even the 1000 is enough, it’s certain that connecting everything to a single filter it’s not the best course to take: separating sources from power amps is always a “healty” practice toward highest possible quality.